Deatailed information for gene ENSG00000280433

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  • Basic information
  • CohesinDB ID: CDBG00056228
  • Gene Symbol: FP565260.6
  • Ensembl ID: ENSG00000280433
  • Gene locus: chr21:5157011-5165472 Strand: -
  • Gene type: protein_coding
  • Double-evidenced cohesin related CRMs
  • Whether cohesin-related CRMs (double-evidenced): True
  • All evidenced type: Interaction,DEGs,
  • Regulatory cohesin (double-evidenced): chr21-5153420-5155308, chr21-5158203-5158553, chr21-5165842-5166183,
  • Co-expression with cohesin genes Rho = 0.4269 FDR = 0.0000
    (Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
  • Tissue specificity
  • Gene expression across tissues (TPM):
  • Tissue specificity of gene (Gini-coefficient): 0.209
    0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
  • Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.830
    0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
  • Cohesin-loop evidence
  • Whether has cohesin-loop: True
  • Involved cell types for loop evidence: SARS-Cov2-olfactory,GM12878,CyT49-endoderm,HCT-116,Hep-G2,IMR-90,K-562,HAP1,CyT49-pancreatic,HFFc6,HeLa-S3,H9-hESC,CyT49-hESC
  • Related loop: chr21:5150000-5175000~~chr21:44000000-44025000, chr21:5150000-5175000~~chr21:44075000-44100000, chr21:5150000-5175000~~chr21:44100000-44125000,
  • Cohesin-loop type: HiC,Direct
  • Cohesin-loop study: 4DNFI5CGQ46V, 4DNFITUOMFUQ, 4DNFI5SUHCGZ, 4DNFIEYQ5ZIR, 4DNFIBCIA62Q, 4DNFIKYXMF1E, 4DNFIYD8LO9Z, 4DNFICSTCJQZ, 4DNFICEGAHRC, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, 4DNFI3A3VYWU, Direct, 4DNFIYDBBSE3, 4DNFI6JJQKFJ, 4DNFIK61ILGM, 4DNFIEJEFCAM, 4DNFIQRTP7NM, 4DNFI9815EEJ, 4DNFIOCW5AEM, 4DNFI9ZWZ5BS, 4DNFI7XAZNNQ, 4DNFIJ8JKKWJ, 4DNFIP71EWXC, 4DNFIS5F6EBL, 4DNFIH7TH4MF, 4DNFII84FBKM
  • Cohesin-loop subunit: Other
  • Cohesin-DEGs evidence
  • Whether cohesin DEGs: True
  • Involved cell types for DEG evidence: SLK,HeLa-S3,P3HR-1
  • Cohesin-DEGs, number of studies: 3
  • Cohesin-DEGs, study: GSE140651,GSE138937,GSE130558
  • Cohesin-DEGs, subunit: WAPL,CTCF,SMC1
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