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Basic information

CohesinDB ID: CDBP00412215

Locus: chr21-7257327-7261424

Data sourse: GSE76815, GSE98367, GSE132649, GSE25021, GSE94872, GSE131577, ENCSR000EHW, GSE101921, GSE135093, GSE206145-NatGen2015, ENCSR635OSG, GSE73207, GSE145327, GSE126755, ENCSR000DYE

Cell type: MCF-7, T-47D, HMEC, Fibroblast, HL-60, TF-1, A-549, HUVEC, IMR-90, CNCC-WT33iPSC, SK-N-SH, Liver, Neutrophil, Macrophage, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.833

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 44% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: ".": 100%, "NotApplicable": 0%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, LCORL, NME2, XBP1, SNAPC4, FOXA1, SUZ12, SNAI1, ZBTB7B, HDGF, CDK2, LYL1, BMI1, ATF3, SETX, ZBTB5, PRDM1, ZNF322, ZNF444, SMARCE1, PAX5, TP63, MZF1, ZNF320, SFPQ, ZNF467, MAF, JMJD1C, SNAPC1, TRIM28, ZNF121, TEAD1, LMO2, ESR1, OCA2, ZNF571, CTCF, TCF12, JUN, EP300, E4F1, ARID5B, MNT, ZNF260, KLF1, GATA6, DPF2, TRIM24, SOX6, RAD51, ZNF512B, ZNF350, ZNF280A, TEAD4, PLRG1, EHMT2, EED, PDX1, YBX1, RBPJ, GLIS1, POU2F2, CHD8, NANOG, BRD1, BRD3, ZNF263, TOP2A, ID3, RUNX1T1, CTBP1, ZBTB1, ZNF317, POU5F1, MYCN, NONO, MLLT3, ZNF563, DDX5, NBN, ERG2, PHB2, TBP, ERG, ZBTB21, ASCL1, OGG1, ZNF341, ETS1, MCM5, EZH1, MYC, RFX1, RAD21, GRHL3, KLF12, FOXK2, GABPA, ZNF8, STAT3, NKX3-1, IKZF1, RCOR1, ZNF667, NFE2, NFRKB, VDR, NR3C1, CEBPB, ZNF750, STAT5B, CREB1, CCAR2, EPAS1, EZH2, ZNF669, WDR5, JMJD6, GRHL2, FEZF1, ARHGAP35, TRPS1, HES1, SPI1, IRF1, ZBTB14, HDAC2, GATA2, INTS13, ZNF644, GATAD2B, ZNF146, FLI1, ATM, RELB, ZNF582, NCOA2, ZIM3, ZNF554, ZNF76, RUNX1, SMC1A, CEBPA, NKX2-2, LDB1, CRY1, AFF4, ZFX, POU4F2, ZNF454, HDAC1, SMAD3, ZBTB12, ZNF770, ERG3, TBX3, MCM2, TRIM22, ZNF549, ZNF18, IRF2, RARA, CREBBP, ZNF384, CDK6, OSR2, ZNF184, NFIB, ARNT, SOX11, MAFB, SP2, FOS, CDK8, SUPT5H, GTF3A, MED1, TERF1, MYB, ZNF331, PIAS1, SMAD1, ZBTB18, NCOA1, ZNF41, EVI1, ZNF37A, STAT5A, ZNF22, SP1, NIPBL, TFAP2A, HNF4A, BCL11A, PHF20, REST, ARID1A, ATF7, FOXP1, PRDM6, SMC3, ELL2, MLLT1, STAG1, ZNF394, ZNF816, PPARG, FOXA2, MTA3, EBF1, ZNF207, NFATC1, CBX3, GTF2B, ZNF662, ZBTB33, MEF2C, ZNF574, CDK9, YY2, HOXB13, ZKSCAN1, KLF7, KDM1A, YY1, RELA, TARDBP, NEUROD1, ZNF282, MCM3, HIF1A, GATA3, KLF15, TAL1, NRIP1, ZNF143, ZNF449, GATA1, TLE3, ZNF592, NCOA3, IRF5, ZNF687, PKNOX1, TP53, NFKB1, ZSCAN22, ZNF140, BRD2, T, ARRB1, AR, ZBTB40, RXR, YAP1, ZNF324, EGLN2, ZNF280D, HSF1, MYNN, NOTCH3, BRD4, JUND, ZBTB26, CLOCK, SCRT1, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00412215