- Basic information
- CohesinDB ID: CDBP00412323
- Locus: chr21-7924676-7926797
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Data sourse: ENCSR000BLD, GSE104888, GSE72082, ENCSR000FAD, GSE132649, ENCSR000EGW, GSE73207, GSE103477, GSE111537, GSE108869, GSE115602, ENCSR000BTU, GSE138405, GSE76893, GSE152721, GSE135093, GSE206145-NatGen2015, GSE120943, GSE116344, GSE106870, GSE145327, ENCSR000EEG, GSE76815, GSE115248, GSE98367, GSE155828, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, ENCSR054FKH, ENCSR153HNT, GSE50893, GSE126755, GSE131577
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Cell type: MDM, RH4, GM10847, GM19240, OCI-AML-3, Transformed-RPE1, H9-hESC, B-cell, GM2630, RPE, Fibroblast, Ishikawa, Kelly, HeLa-S3, IMR-90, K-562, GM18526, H1-hESC, Monocytes, GM18505, TF-1, GM12878, GM12891, HUES9, SK-N-SH, GM19239, GM19193, HAP1, GM19099, Macrophage, MCF-7, GM12892, T-47D, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, A-549, GM19238, HeLa, CNCC-WT33iPSC, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 19% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.511
- Subunit: NIPBL,NIPBL-antibody2,SA1,Rad21,NIPBL-antibody1,SMC1,SA2,Mau2,NIPBL-antibody4,SMC3,NIPBL-antibody3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
50% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
".": 100%,
"NotApplicable": 0%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: YBX1, TRP47, PLRG1, CHD8, FOXA2, LCORL, TOP2A, CTBP1, GTF2B, DUX4, FOXA1, NONO, TBX3, SUZ12, NBN, ARID3A, TRIM22, PHB2, ZKSCAN1, RELA, HDGF, BMI1, MCM5, MYC, ZNF282, MCM3, PRDM1, ARNT, HIF1A, FOXK2, ATF2, ZNF8, IKZF1, NFRKB, VDR, NR3C1, BCLAF1, CREB1, EZH2, LMO2, IRF5, PKNOX1, ESR1, TCF12, SP1, E4F1, HES1, MNT, AR, HDAC2, ZBTB40, PRDM4, GATAD2B, TAF9B, SOX6, ZNF280D, RAD51, ATF7, ATM, BRD4, FOXP1, MLLT1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:5225000-5250000~~chr21:7925000-7950000,
chr21:7250000-7275000~~chr21:7925000-7950000,
chr21:7925000-7950000~~chr21:10325000-10350000,
chr21:7925000-7950000~~chr21:10425000-10450000,
chr21:7925000-7950000~~chr21:10650000-10675000,
chr21:7925000-7950000~~chr21:10700000-10725000,
chr21:7925000-7950000~~chr21:10800000-10825000,
chr21:7925000-7950000~~chr21:8025000-8050000,
chr21:7925000-7950000~~chr21:8675000-8700000,
chr21:7925000-7950000~~chr21:9225000-9250000,
chr21:7925000-7950000~~chr21:9725000-9750000,