- Basic information
- CohesinDB ID: CDBP00412424
- Locus: chr21-8786700-8788788
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE98367, GSE132649, GSE206145-NatGen2015, GSE62063, ENCSR153HNT, GSE116344
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Cell type: MCF-7, T-47D, Fibroblast, HCT-116, RH4, K-562, HSPC, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 56%,
"9_Het": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): TPTE,TEKT4P2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 110
- Related genes and loops
- Related gene:
ENSG00000274391,
ENSG00000188681,
- Related loop:
chr21:5225000-5250000~~chr21:8775000-8800000,
chr21:8775000-8800000~~chr21:10325000-10350000,
chr21:8775000-8800000~~chr21:10425000-10450000,
chr21:8775000-8800000~~chr21:10575000-10600000,
chr21:8775000-8800000~~chr21:9000000-9025000,
chr21:8775000-8800000~~chr21:9100000-9125000,
chr21:8775000-8800000~~chr21:9350000-9375000,
chr21:8775000-8800000~~chr21:9750000-9775000,