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Basic information

CohesinDB ID: CDBP00412476

Locus: chr21-8996055-8996475

Data sourse: GSE76893, GSE67783

Cell type: A-549, HSPC, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "9_Het": 48%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, SMARCA2, HMG20A, SOX2, NME2, MEIS2, XBP1, KDM4B, FOXA1, SUZ12, PBX2, UBTF, SRSF4, HNRNPK, TFAP4, ZNF274, ATF3, CDK7, ZFP64, HNRNPUL1, THAP1, SETX, CHD7, PRDM1, CTCFL, MXD4, CDC5L, CDX2, JMJD1C, KLF5, ELF1, TEAD1, TRIM28, RBM39, KLF6, KLF10, ESR1, OCA2, MED26, MLL, HDAC8, MBD4, FUS, CTCF, TCF12, JUN, EP300, E4F1, BAF155, L3MBTL4, ZNF75A, GATA6, ZNF695, SOX5, PYGO2, MNT, E2F6, SIX5, SOX6, E2F4, CREB3, DDX20, U2AF2, E2F1, ZNF528, TEAD4, FOXA3, ZNF175, GTF2F1, PDX1, TFAP2C, EED, ATRX, GATAD2A, GLIS1, POU2F2, NANOG, BRD1, ZSCAN5D, POU5F1, MYCN, TOP2A, ZNF263, KDM4C, CHD8, CTBP1, RUNX1T1, DUX4, ZSCAN5A, STAT1, ZBTB48, NONO, SRF, BAHD1, ARID3A, ERG2, TBP, ERG, CHD4, USP7, ASCL1, ZNF341, ETS1, MYC, EZH1, ZKSCAN2, HOMEZ, TOP1, RAD21, GRHL3, RXRA, NKX2-1, FOXK2, PROX1, GABPA, STAT3, XRCC5, SOX10, APC, NKX3-1, IKZF1, MIER3, DNMT3B, HNRNPH1, RCOR1, ARNTL, VDR, NR3C1, CEBPB, ZNF639, DACH1, HNRNPL, NR2F6, NFRKB, ZBTB11, CCAR2, CREB1, EZH2, TBL1XR1, EPAS1, KLF8, GRHL2, TRPS1, GABPB1, ZHX2, SPI1, HES1, KDM5A, IRF1, HDAC2, SSRP1, GATA2, ZNF644, MXD3, FLI1, HCFC1, NFIL3, NCOA2, ZNF76, ATF1, PTBP1, ETV5, RUNX1, THAP11, CBX1, ZBTB24, CEBPA, EZH2phosphoT487, SMC1A, CRY1, FIP1L1, SIN3A, AFF4, ZFX, SOX13, POU4F2, PCBP2, SMAD3, NMYC, ZNF18, SMARCC1, CEBPZ, CREBBP, PRPF4, IRF2, ZNF384, EWSR1, TAF15, GATA4, GR, FANCD2, NRF1, ARNT, TFDP1, BACH1, ELK1, ZNF48, HMBOX1, SMAD4, PBX3, MAFB, ETV6, CHD1, CDK8, FOS, SNRNP70, NR2C1, MED1, SP2, GMEB1, ZEB1, PML, SPDEF, MYB, PIAS1, U2AF1, SMAD1, ZMYM3, KLF9, NCOA1, ELL, SETDB1, STAT5A, ZNF22, RBM22, USF1, NIPBL, MAFK, SP1, BCL11A, HNF4A, PHF20, IKZF5, REST, ZBTB7A, ARID1A, ZHX1, ATF7, SALL4, HNRNPLL, SRSF9, NKX2-2, BCOR, FOXP1, AFF1, SMC3, ELL2, NCOR2, STAG1, ETV4, NFATC3, ZNF283, NCOA4, MEF2B, PPARG, FOXA2, TBL1X, CBX3, BRF2, PAF1, CREM, GTF2B, MAFF, WT1, ZBED1, ZBTB33, CDK9, HOXB13, ZKSCAN1, BCL3, KDM1A, YY1, RELA, ZNF589, FOXO3, NEUROD1, ZNF148, BRG1, BRCA1, SP140, ZFP36, SKIL, HIF1A, ISL1, GATA3, TAL1, MAX, NRIP1, GATA1, ZNF143, HAND2, TLE3, CEBPG, BCL6, NCOA3, ZKSCAN8, TCF7L2, TP53, PKNOX1, IRF5, ZSCAN22, EGR2, PHOX2B, BRD2, T, ARRB1, ARID4B, AR, PAX3-FOXO1, TAF1, ZBTB16, ZBTB40, RXR, EGLN2, RB1, HSF1, RNF2, ZBTB26, JUND, BRD4, NOTCH3, CLOCK, CUX1, MAZ, ILF3, TBX2, MEF2D, ZNF24, ZFP42, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 14

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00412476