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Basic information

CohesinDB ID: CDBP00412485

Locus: chr21-9015219-9019636

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, GSE72082, ENCSR000FAD, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE111537, GSE131606, GSE25021, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE206145-NatGen2015, GSE120943, GSE112028, GSE116344, GSE94872, GSE118494, ENCSR000EEG, GSE98367, GSE168045, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, GSE55407, ENCSR167MTG, GSE110061, GSE129526, GSE111913, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE126755, GSE38411

Cell type: RH4, OCI-AML-3, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, IMR-90, K-562, BCBL-1, DKO, H1-hESC, Monocytes, GM12878, SK-N-SH, RT-112, HeLa-Tet-On, THP-1, Macrophage, MCF-7, Hela-Kyoto, HCT-116, SC, Hep-G2, HUVEC, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 16% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.700

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "9_Het": 40%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, RELA, NOTCH1, MYB, PAF1, KDM4C, TCF7L2, ESR1, NOTCH3, CDK8, APC, BRD2, NIPBL

Target gene symbol (double-evidenced CRMs): TPTE

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 80

Related genes and loops

Related gene: ENSG00000274391,

eachgene

Deatailed information for cohesin site CDBP00412485