- Basic information
- CohesinDB ID: CDBP00412559
- Locus: chr21-9246096-9254013
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Data sourse: GSE118494, GSE122299, GSE98367, GSE132649, GSE25021, GSE94872, GSE101921, GSE135093, GSE62063, GSE120943, ENCSR153HNT, GSE206145-NatGen2015, GSE112028, GSE116344, GSE145327, GSE50893, GSE126755, GSE73207
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Cell type: RH4, H9-hESC, HMEC, Fibroblast, IMR-90, K-562, Monocytes, TF-1, GM12878, HeLa-Tet-On, CNCCs-H9ESC, Macrophage, Ramos, MCF-7, T-47D, HEK293T, HUVEC, CNCC-WT33iPSC, Neutrophil
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.789
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 38%,
"15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, CREBBP, OGG1, MYC, TRIM28, IRF4, CRY1, TERF1, TOP2A, EZH2, XBP1, GTF2B, BRD4, NOTCH3, OCA2, CLOCK, NONO, MAF1, NRIP1, NFE2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 191
- Related genes and loops
- Related gene:
- Related loop:
chr21:6350000-6375000~~chr21:9225000-9250000,
chr21:6350000-6375000~~chr21:9250000-9275000,
chr21:7250000-7275000~~chr21:9225000-9250000,
chr21:7925000-7950000~~chr21:9225000-9250000,
chr21:7950000-7975000~~chr21:9225000-9250000,
chr21:8850000-8875000~~chr21:9250000-9275000,
chr21:9150000-9175000~~chr21:9250000-9275000,
chr21:9225000-9250000~~chr21:10250000-10275000,
chr21:9225000-9250000~~chr21:10325000-10350000,
chr21:9225000-9250000~~chr21:10400000-10425000,
chr21:9225000-9250000~~chr21:10450000-10475000,
chr21:9225000-9250000~~chr21:10650000-10675000,
chr21:9225000-9250000~~chr21:10700000-10725000,
chr21:9225000-9250000~~chr21:10750000-10775000,