- Basic information
- CohesinDB ID: CDBP00412702
- Locus: chr21-9758865-9759713
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015, GSE62063, GSE83726
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Cell type: RPE, Fibroblast, RH4, HCT-116, RT-112, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
".": 100%,
"NotApplicable": 0%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, HNF1A, XBP1, FOXA1, SUZ12, ATF3, MITF, KLF5, ELF1, TRIM28, TEAD1, ESR1, MLL, OCA2, CTCF, JUN, E2F1, TFAP2C, EED, POU2F2, CHD8, BRD1, ZNF425, MYCN, RUNX1T1, KDM4C, ZBTB48, ZSCAN5A, STAT1, HOXB7, ERG, ASCL1, MYC, EZH1, RAD21, GRHL3, FOXK2, GABPA, NKX3-1, HNRNPH1, TERF2, VDR, NR3C1, CEBPB, CREB1, EZH2, GRHL2, SPI1, IRF1, INTS13, GATA2, MXD3, FLI1, NCOA2, PTBP1, AHRR, SMC1A, CEBPA, EZH2phosphoT487, LDB1, SIN3A, ZFX, NFKBIA, POU4F2, SMAD3, TET2, CBX8, CREBBP, ARNT, CDK8, MED1, PIAS1, SETDB1, BCL11A, REST, SMC3, STAG1, NFATC3, CBFA2T2, PPARG, ZNF207, TBL1X, BRF2, GTF2B, WT1, HOXB13, RELA, TARDBP, SP140, HIF1A, GATA3, NRIP1, ZNF143, GATA1, CBX2, KLF4, NCOA3, NR2F1, NEUROG2, ARRB1, AR, EGLN2, HEXIM1, RB1, HSF1, NOTCH3, BRD4, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): TPTE
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000274391,
- Related loop:
chr21:5225000-5250000~~chr21:9750000-9775000,
chr21:5250000-5275000~~chr21:9750000-9775000,
chr21:5375000-5400000~~chr21:9750000-9775000,
chr21:7250000-7275000~~chr21:9750000-9775000,
chr21:7950000-7975000~~chr21:9750000-9775000,
chr21:8025000-8050000~~chr21:9750000-9775000,
chr21:8775000-8800000~~chr21:9750000-9775000,
chr21:8975000-9000000~~chr21:9750000-9775000,
chr21:9550000-9575000~~chr21:9750000-9775000,
chr21:9650000-9675000~~chr21:9750000-9775000,
chr21:9750000-9775000~~chr21:10000000-10025000,
chr21:9750000-9775000~~chr21:10100000-10125000,
chr21:9750000-9775000~~chr21:10325000-10350000,
chr21:9750000-9775000~~chr21:10350000-10375000,
chr21:9750000-9775000~~chr21:10400000-10425000,
chr21:9750000-9775000~~chr21:10575000-10600000,
chr21:9750000-9775000~~chr21:10625000-10650000,
chr21:9750000-9775000~~chr21:10750000-10775000,
chr21:9750000-9775000~~chr21:10775000-10800000,
chr21:9750000-9775000~~chr21:13000000-13025000,
chr21:9750000-9775000~~chr21:9850000-9875000,