- Basic information
- CohesinDB ID: CDBP00412832
- Locus: chr21-10269793-10271526
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Data sourse: ENCSR000BLD, GSE72082, ENCSR501LQA, GSE132649, ENCSR760NPX, ENCSR404BPV, ENCSR150EFU, ENCSR330ELC, ENCSR000EDW, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE152721, ENCSR806UKK, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, ENCSR199XBQ, GSE106870, GSE116344, GSE145327, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR635OSG, ENCSR767DFK, ENCSR981FDC, GSE62063, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, GSE50893, ENCSR748MVX, ENCSR481YWD
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Cell type: RH4, CVB-hiPSC, CVI-hiPSC, Liver, H9-hESC, RPE, Fibroblast, H1-hESC, Monocytes, GM12891, GM19239, Macrophage, Ramos, HUES64, T-47D, HEK293T, Hep-G2, Neurons-H1, A-549, CNCC-WT33iPSC, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 20% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.767
- Subunit: NIPBL,NIPBL-antibody2,SA1,Rad21,SMC1,SA2,SMC3,NIPBL-antibody3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
26% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
".": 100%,
"NotApplicable": 0%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, POU2F2, PGR, HDAC1, PPARG, LDB1, CDK7, CHD8, NME2, POU4F2, ZMYND11, GTF2B, SMAD3, FOXA1, MLLT3, SUZ12, HOXB13, ERG, TFAP4, RELA, CREBBP, ASCL1, MYC, RAD21, GRHL3, HIF1A, CBFB, GATA3, SMC3, GABPA, TAL1, STAT3, MAX, NRIP1, FOS, NKX3-1, ZNF143, HDAC3, VDR, CSNK2A1, NR3C1, RFX2, JMJD1C, NCOA3, SNAPC1, KLF5, ELF1, CREB1, EPAS1, EZH2, ESR1, MLL, CTCF, JUN, TCF12, EP300, NIPBL, ARRB1, HNF4A, AR, SPI1, BCL11A, MAFK, HDAC2, RXR, GATA2, FOXA2, FLI1, ASH2L, HSF1, RNF2, BRD4, AFF1, JUND, NR1H3, NR5A2, NCOA2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
- Related loop:
chr21:10100000-10125000~~chr21:10250000-10275000,
chr21:10250000-10275000~~chr21:10350000-10375000,
chr21:10250000-10275000~~chr21:10400000-10425000,
chr21:10250000-10275000~~chr21:10425000-10450000,
chr21:10250000-10275000~~chr21:10450000-10475000,
chr21:10250000-10275000~~chr21:13000000-13025000,
chr21:8750000-8775000~~chr21:10250000-10275000,
chr21:8975000-9000000~~chr21:10250000-10275000,
chr21:9000000-9025000~~chr21:10250000-10275000,
chr21:9225000-9250000~~chr21:10250000-10275000,