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Basic information

CohesinDB ID: CDBP00412834

Locus: chr21-10324288-10326453

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE132649, ENCSR760NPX, ENCSR404BPV, ENCSR150EFU, GSE103477, GSE25021, ENCSR330ELC, ENCSR000EDW, ENCSR000BUC, ENCSR000DYE, ENCSR000EFJ, ENCSR917QNE, GSE165895, ENCSR000EAC, ENCSR000BKV, GSE101921, ENCSR806UKK, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, ENCSR199XBQ, GSE106870, GSE116344, GSE145327, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR635OSG, ENCSR767DFK, ENCSR981FDC, GSE62063, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, GSE50893, ENCSR748MVX, ENCSR481YWD

Cell type: MDM, RH4, CVB-hiPSC, CVI-hiPSC, Liver, H9-hESC, B-cell, RPE, Fibroblast, IMR-90, K-562, HFFc6, H1-hESC, Monocytes, GM12878, GM12891, HUES9, GM19239, Macrophage, HUES64, MCF-7, Ramos, T-47D, MCF-10A, Hep-G2, Neurons-H1, A-549

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 29% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.700

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 26% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "8_ZNF/Rpts": 45%, "9_Het": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF274, MYC, NKX2-2, ONECUT1, TOP1, NCOA2, MAFB, NKX3-1, ZNF639

Target gene symbol (double-evidenced CRMs): TPTE

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000274391,

eachgene

Deatailed information for cohesin site CDBP00412834