- Basic information
- CohesinDB ID: CDBP00412855
- Locus: chr21-10377614-10381787
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE98367, GSE111913, GSE206145-NatGen2015, GSE120943
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Cell type: MCF-7, Fibroblast, HCT-116, Monocytes, RT-112, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
26% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"9_Het": 45%,
"8_ZNF/Rpts": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CREBBP, CEBPB, MAF, SMC1A, CHD8, CTCFL, NME2, TP53, ESR1, TP63
- Target gene symbol (double-evidenced CRMs): TPTE
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 216
- Related genes and loops
- Related gene:
ENSG00000274391,
- Related loop:
chr21:10250000-10275000~~chr21:10350000-10375000,
chr21:10350000-10375000~~chr21:10450000-10475000,
chr21:10350000-10375000~~chr21:10725000-10750000,
chr21:10350000-10375000~~chr21:10750000-10775000,
chr21:10350000-10375000~~chr21:10775000-10800000,
chr21:10350000-10375000~~chr21:10800000-10825000,
chr21:10350000-10375000~~chr21:13000000-13025000,
chr21:10350000-10375000~~chr21:13800000-13825000,
chr21:10375000-10400000~~chr21:10525000-10550000,
chr21:10375000-10400000~~chr21:10550000-10575000,
chr21:5200000-5225000~~chr21:10350000-10375000,
chr21:5225000-5250000~~chr21:10350000-10375000,
chr21:5225000-5250000~~chr21:10375000-10400000,
chr21:7250000-7275000~~chr21:10350000-10375000,
chr21:7950000-7975000~~chr21:10350000-10375000,
chr21:8675000-8700000~~chr21:10350000-10375000,
chr21:8750000-8775000~~chr21:10350000-10375000,
chr21:9650000-9675000~~chr21:10350000-10375000,
chr21:9750000-9775000~~chr21:10350000-10375000,
chr21:9875000-9900000~~chr21:10350000-10375000,