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Basic information

CohesinDB ID: CDBP00412872

Locus: chr21-10425921-10427107

Data sourse: GSE206145-GSE177045, GSE67783, GSE98367, GSE25021, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE145327, GSE50893

Cell type: MCF-7, RPE, Fibroblast, Monocytes, GM12878, K-562, HSPC, Macrophage, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: False

Compartment: 26% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "9_Het": 65%, "8_ZNF/Rpts": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, PPARG, GTF2B, FOXA1, HOXB13, ERG, RELA, MYC, GRHL3, HIF1A, GABPA, TAL1, FOS, CDK8, NR3C1, NCOA3, TRIM28, PIAS1, EZH2, ESR1, OCA2, CTCF, SP1, SPI1, AR, GATA6, RXR, FLI1, HSF1, BRD4, STAG1

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00412872