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Basic information

CohesinDB ID: CDBP00412898

Locus: chr21-10465427-10466183

Data sourse: GSE118494, GSE206145-GSE177045, GSE67783, GSE86191, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE83726, GSE145327

Cell type: MCF-7, RPE, Fibroblast, HCT-116, RH4, RT-112, IMR-90, K-562, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 26% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "9_Het": 68%, "8_ZNF/Rpts": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, SMC1A, POU5F1, MYCN, ZNF263, KDM4C, POU4F2, XBP1, NFKBIA, ZBTB48, STAT1, TET2, RELA, CREBBP, MYC, SP140, HIF1A, NRIP1, PRDM14, HNRNPH1, NCOA3, NR2F1, ESR1, OCA2, NCOA1, CTCF, AR, NOTCH3, BRD4, SMC3

Target gene symbol (double-evidenced CRMs): TPTE

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000274391,

eachgene

Deatailed information for cohesin site CDBP00412898