- Basic information
- CohesinDB ID: CDBP00412917
- Locus: chr21-10520357-10522612
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Data sourse: GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE116868, GSE111913, GSE115602, GSE206145, GSE206145-NatGen2015, GSE68388, ENCSR703TNG, GSE25021, GSE165895
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, MB157, RT-112, HSPC, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 60%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRP47, CHD8, FOXA2, MYCN, POU5F1, ZFX, WT1, ZBTB33, ERG, RELA, OGG1, ATF3, SP140, GRHL3, GATA3, STAT3, MAF1, MED1, PLAG1, NCOA3, TRIM28, ESR1, CTCF, ZHX2, AR, PAX8, PCBP1, RXR, TRIM24, FLI1, BRD4, E2F1, AATF, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): TPTE
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 136
- Number of somatic mutations (non-coding): 43
- Related genes and loops