- Basic information
- CohesinDB ID: CDBP00412954
- Locus: chr21-10655332-10655803
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Data sourse: GSE145327, GSE76815, GSE98367, GSE152721, GSE135093, GSE206145-NatGen2015, GSE120943, GSE111537, GSE106870, GSE116344, GSE126755, GSE131577
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Cell type: Fibroblast, HL-60, Monocytes, RH4, OCI-AML-3, HUES9, IMR-90, SK-N-SH, Neutrophil, HAP1, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 50%,
"8_ZNF/Rpts": 48%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, LCORL, XBP1, FOXA1, SUZ12, ZBTB7B, HDGF, BMI1, TEAD1, BCLAF1, TRIM28, MCM7, ESR1, CTCF, TCF12, JUN, E4F1, MNT, PAX8, DPF2, PRDM4, SOX6, RAD51, ZNF512B, PLRG1, YBX1, TOP2A, ID3, CTBP1, MTA2, STAT1, NONO, NBN, ARID3A, PHB2, ERG, HOXC5, MCM5, RFX1, FOXK2, STAT3, ZNF8, IKZF1, NFRKB, ESRRA, EZH2, GRHL2, HES1, SPI1, IRF1, HDAC2, INTS13, GATAD2B, TAF9B, ATM, TBX3, MCM2, TRIM22, NFIB, ARNT, NRF1, ZNF48, ATF2, CDK8, SP1, ARID2, ATF7, FOXP1, MLLT1, TRP47, FOXA2, MTA3, ZNF207, ZNF600, GTF2B, ZBTB33, ZKSCAN1, RELA, TARDBP, NEUROD1, ZNF282, MCM3, SP140, GATA3, NRIP1, ZNF592, NCOA3, ZNF530, IRF5, PKNOX1, AR, ZBTB16, ZBTB40, EGLN2, HSF1, BRD4, BRCA1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops