- Basic information
- CohesinDB ID: CDBP00412978
- Locus: chr21-10716568-10716874
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Data sourse: GSE206145-NatGen2015, GSE135093, GSE112028, GSE145327, GSE80989
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Cell type: Fibroblast, VU1199-F, IMR-90, CNCC-WT33iPSC, HeLa-Tet-On
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,Rad21,SA2,ESCO2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"8_ZNF/Rpts": 64%,
"9_Het": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: LCORL, NME2, XBP1, FOXA1, SUZ12, HNRNPK, ZBTB7B, HDGF, BMI1, INSM2, ZBTB5, PRDM1, ZNF444, TP63, TEAD1, TRIM28, BCLAF1, MCM7, ESR1, CTCF, TCF12, E4F1, MNT, PYGO2, DPF2, PRDM4, SOX6, RAD51, ZNF512B, PLRG1, EHMT2, YBX1, TOP2A, CTBP1, MTA2, ZBTB1, DUX4, STAT1, NONO, NBN, ARID3A, PHB2, ERG, OGG1, EZH1, MCM5, MYC, RFX1, ZNF671, GRHL3, FOXK2, ZNF8, STAT3, IKZF1, RCOR1, NFRKB, NR3C1, ESRRA, CEBPB, CREB1, CCAR2, EZH2, HES1, SPI1, HDAC2, INTS13, GATAD2B, TAF9B, ATM, CIITA, CEBPA, HDAC1, ZFX, TBX3, MCM2, TRIM22, CREBBP, ZNF384, NFIB, ARNT, NRF1, ATF2, ZNF48, ETV6, SETDB1, SP1, BCL11A, ARID2, ARID1A, ATF7, FOXP1, STAG1, MLLT1, TRP47, NCOA4, ZNF207, MTA3, FOXA2, ZNF600, ZBTB33, HOXB13, ZKSCAN1, RELA, TARDBP, NEUROD1, ZNF282, MCM3, SP140, ZNF592, NCOA3, IRF5, ZNF687, PKNOX1, ZNF140, ZBTB40, YAP1, HEXIM1, BRD4, ZNF24
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops