- Basic information
- CohesinDB ID: CDBP00413192
- Locus: chr21-14070030-14074512
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BLY, GSE105028, GSE25021, GSE131606, GSE67783, GSE86191, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, GSE116344, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000EHX, ENCSR000BTQ, GSE111913, GSE68388, GSE83726, GSE38411
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Monocytes, RH4, DKO, RT-112, SK-N-SH, BCBL-1, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 40%,
"9_Het": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, TRIM25, CBX1, FOXA2, MYCN, ZNF263, AGO1, ZFX, ZBTB48, WT1, FOXA1, TET2, ZBTB33, LEO1, ZNF28, ERG, YY1, RELA, CREBBP, OGG1, ATF3, MYC, CTCFL, RAD21, SP140, NFIB, ARNT, ZNF444, NRF1, CBFB, GRHL3, STAT3, MAX, TP63, NRIP1, PRDM14, AGO2, CHD1, MED1, NR3C1, TEAD1, TRIM28, RBM39, NR2F1, EZH2, ESR1, PKNOX1, OCA2, CTCF, RBM22, ZHX2, AR, RXR, EGR1, HEXIM1, TFIIIC, HSF1, BRD4, MAZ, AATF, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 74
- Related genes and loops
- Related gene:
ENSG00000155307,
- Related loop:
chr21:13500000-13525000~~chr21:14050000-14075000,
chr21:13875000-13900000~~chr21:14050000-14075000,
chr21:13975000-14000000~~chr21:14075000-14100000,
chr21:14050000-14075000~~chr21:14475000-14500000,
chr21:14075000-14100000~~chr21:15025000-15050000,
chr21:14075000-14100000~~chr21:15725000-15750000,
chr21:14075000-14100000~~chr21:17600000-17625000,
chr21:14075000-14100000~~chr21:17775000-17800000,
chr21:6875000-6900000~~chr21:14050000-14075000,