- Basic information
- CohesinDB ID: CDBP00413204
- Locus: chr21-14115777-14116583
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Data sourse: GSE93080, ENCSR000DZP, GSE67783, ENCSR000BMY, GSE50893
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Cell type: GM2630, GM2610, GM12878, GM2255, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 74%,
"9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, CBFA2T2, MEF2B, SMC1A, EBF1, CREM, ZFX, MTA2, ZBTB48, NBN, LEO1, TRIM22, YY1, RELA, HDGF, MYC, RUNX3, PRDM1, RAD21, HIF1A, SKIL, BATF, PAX5, ETV6, IKZF1, MED1, BCLAF1, EZH2, ZNF687, OCA2, GRHL2, SETDB1, RBM22, SND1, BCL11A, TCF12, TBX21, BHLHE40, SPI1, IRF1, AR, IRF4, EGR1, ATF7, RB1, ASH2L, HCFC1, IKZF2, BRD4, RELB, SMC3, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155304,
- Related loop:
chr21:13000000-13025000~~chr21:14100000-14125000,
chr21:13450000-13475000~~chr21:14100000-14125000,
chr21:13800000-13825000~~chr21:14100000-14125000,
chr21:13805524-13807565~~chr21:14118402-14121049,
chr21:13806384-13807544~~chr21:14119421-14121216,
chr21:13850000-13875000~~chr21:14100000-14125000,
chr21:13875000-13900000~~chr21:14100000-14125000,
chr21:14100000-14125000~~chr21:14375000-14400000,
chr21:14100000-14125000~~chr21:15150000-15175000,