- Basic information
- CohesinDB ID: CDBP00413205
- Locus: chr21-14117430-14121451
-
Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE86191, GSE101921, ENCSR806UKK, GSE51234, ENCSR198ZYJ, GSE130135, ENCSR895JMI, ENCSR000EEG, GSE115248, ENCSR247LSH, GSE105004, GSE155324, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE131577, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, ENCSR000ECE, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR153HNT, GSE68388, GSE126990
-
Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, Ishikawa, Kelly, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, THP-1, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, GM19238, HeLa, CNCC-WT33iPSC, TC-71, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 56% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.289
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 73%,
"9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RBM22, BCL11A
- Target gene symbol (double-evidenced CRMs): HSPA13
- Function elements
- Human SNPs: Heart_rate_in_heart_failure_with_reduced_ejection_fraction
- Number of somatic mutations (coding): 84
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155304,
- Related loop:
chr21:13000000-13025000~~chr21:14100000-14125000,
chr21:13450000-13475000~~chr21:14100000-14125000,
chr21:13450000-13475000~~chr21:14125000-14150000,
chr21:13550000-13575000~~chr21:14125000-14150000,
chr21:13800000-13825000~~chr21:14100000-14125000,
chr21:13800000-13825000~~chr21:14125000-14150000,
chr21:13805524-13807565~~chr21:14118402-14121049,
chr21:13806384-13807544~~chr21:14119421-14121216,
chr21:13850000-13875000~~chr21:14100000-14125000,
chr21:13875000-13900000~~chr21:14100000-14125000,
chr21:13875000-13900000~~chr21:14125000-14150000,
chr21:14025000-14050000~~chr21:14125000-14150000,
chr21:14100000-14125000~~chr21:14375000-14400000,
chr21:14100000-14125000~~chr21:15150000-15175000,
chr21:14125000-14150000~~chr21:14225000-14250000,