- Basic information
- CohesinDB ID: CDBP00413210
- Locus: chr21-14215832-14216924
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE67783, ENCSR000BKV, GSE86191, GSE116868, GSE111913, ENCSR404BPV, GSE105028, GSE152721, GSE206145-NatGen2015, GSE206145, ENCSR198ZYJ, ENCSR153HNT, GSE25021, GSE50893
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, GM18505, HEK293T, MB157, Neurons-H1, RT-112, HSPC, K-562, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"1_TssA": 27%,
"15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, PGR, FANCL, ZNF280D, ZNF660, SOX2, ZNF616, PATZ1, FOXA1, SUZ12, RBFOX2, ZFHX2, ATF3, BMI1, CTCFL, CHD7, PRDM1, ZNF322, CBFB, ZNF189, MITF, BACH2, INTS11, ZNF629, MAF, ELF1, TRIM28, KLF6, SNAI2, ETV1, SAP30, ESR1, OCA2, MED26, LMO2, ZNF561, CTCF, TCF12, BAF155, E4F1, EP300, MNT, LMO1, RYBP, E2F6, TRIM24, IRF4, E2F4, E2F1, SMC1, TEAD4, GTF2F1, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, BRD1, ZNF263, POU5F1, RUNX1T1, MYCN, KDM4C, CDK7, CTBP1, ZBTB17, ZBTB48, BRD3, STAT1, ZNF134, ERG2, SP4, TBP, ERG, OGG1, ZBTB8A, ETS1, EZH1, MYC, SMARCA4, KDM4A, FOXP2, RAD21, GRHL3, KLF12, GABPA, STAT3, XRCC5, IKZF1, RCOR1, NFE2, SRSF3, STAT5B, KMT2A, CREB1, ZBTB11, EZH2, KLF8, GRHL2, GABPB1, PHF8, SPI1, IRF1, PCBP1, HDAC2, INTS13, GATA2, FLI1, MXI1, HEXIM1-CDK9, MRTFB, ZIM3, ATF1, RUNX1, SMC1A, BCL6, HDAC1, NKX2-2, SIRT6, EZH2phosphoT487, ZNF335, AFF4, SIN3A, ZFX, ZFP37, ZNF770, CBX8, ERG3, SP5, TRIM22, PRDM10, IRF2, NOTCH1, TAF15, ZSCAN30, ZNF184, SP3, ARNT, NRF1, TFDP1, BACH1, ZNF48, PRDM9, ZEB2, NCAPH2, ZNF10, SP2, CHD1, MED1, GMEB1, ZEB1, TEAD3, KDM6B, MYB, ZXDB, KLF9, MAFG, L3MBTL2, C11orf30, MAFK, SP1, BCL11A, GSPT2, NIPBL, REST, ZBTB7A, CCNT2, ATF7, ASH2L, HNRNPLL, PCGF2, PHIP, GLIS2, FOXP1, BCOR, TCF3, AATF, SMC3, STAG1, CXXC4, ZNF394, NELFA, TRP47, FOXA2, MTA3, CREM, RBBP5, TBL1X, ZNF600, GTF2B, WT1, ZBTB33, CDK9, HOXB13, KDM1A, ZNF19, YY1, RELA, NEUROD1, SP140, ZFP36, HIF1A, PCGF1, GATA3, ZNF519, KLF15, MGA, TAL1, MAX, ZNF143, KLF4, BCL11B, SP7, NCOA3, TCF7L2, NR2F1, KDM5B, TP53, ZNF334, NFKB1, EGR2, BRD2, ELF3, AR, KMT2D, TAF1, EGLN2, HEXIM1, RB1, TFIIIC, ZBTB26, RNF2, HSF1, EGR1, ILF3, NOTCH3, JUND, BRD4, MAZ, CLOCK, AHR
- Target gene symbol (double-evidenced CRMs): RBM11
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 33
- Number of somatic mutations (non-coding): 7
- Related genes and loops