- Basic information
- CohesinDB ID: CDBP00413215
- Locus: chr21-14256459-14256802
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
46% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF157, AR, OGG1, DUX4, ZBTB48, FOXA1, ZBTB33, SPI1, ERG
- Target gene symbol (double-evidenced CRMs): USP25,HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155313,
- Related loop:
chr21:14250000-14275000~~chr21:14375000-14400000,
chr21:14250000-14275000~~chr21:14725000-14750000,
chr21:14250000-14275000~~chr21:14750000-14775000,
chr21:14250000-14275000~~chr21:14850000-14875000,
chr21:14250000-14275000~~chr21:15475000-15500000,
chr21:14250000-14275000~~chr21:15575000-15600000,
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14253183-14254696~~chr21:15062247-15066667,
chr21:14258749-14260833~~chr21:14772926-14775113,
chr21:14258819-14260853~~chr21:14861975-14863460,
chr21:14258824-14260829~~chr21:14862240-14865713,
chr21:14258853-14260940~~chr21:14772935-14775155,
chr21:14258859-14260921~~chr21:14737119-14739132,
chr21:14258927-14260903~~chr21:14737109-14739142,
chr21:14259014-14260613~~chr21:15062794-15066469,
chr21:14259015-14260560~~chr21:14773159-14774697,
chr21:14259018-14260746~~chr21:14772993-14774949,
chr21:14259167-14260586~~chr21:14773118-14774714,
chr21:14259193-14260604~~chr21:14862345-14863646,