- Basic information
- CohesinDB ID: CDBP00413216
- Locus: chr21-14257889-14261023
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE139435, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
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Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, HeLa-Tet-On, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, CNCC-WT33iPSC, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 66% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.244
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
46% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RUNX1, ZNF384, ZBTB7A, ZSCAN5D, MYC, EZH2, XBP1, GRHL3, GTF2B, HIF1A, NOTCH3, GATA3, CTCF
- Target gene symbol (double-evidenced CRMs): HSPA13,USP25,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14250000-14275000~~chr21:14375000-14400000,
chr21:14250000-14275000~~chr21:14725000-14750000,
chr21:14250000-14275000~~chr21:14750000-14775000,
chr21:14250000-14275000~~chr21:14850000-14875000,
chr21:14250000-14275000~~chr21:15475000-15500000,
chr21:14250000-14275000~~chr21:15575000-15600000,
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14253183-14254696~~chr21:15062247-15066667,
chr21:14258749-14260833~~chr21:14772926-14775113,
chr21:14258819-14260853~~chr21:14861975-14863460,
chr21:14258824-14260829~~chr21:14862240-14865713,
chr21:14258853-14260940~~chr21:14772935-14775155,
chr21:14258859-14260921~~chr21:14737119-14739132,
chr21:14258927-14260903~~chr21:14737109-14739142,
chr21:14259014-14260613~~chr21:15062794-15066469,
chr21:14259015-14260560~~chr21:14773159-14774697,
chr21:14259018-14260746~~chr21:14772993-14774949,
chr21:14259167-14260586~~chr21:14773118-14774714,
chr21:14259193-14260604~~chr21:14862345-14863646,