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Basic information

CohesinDB ID: CDBP00413218

Locus: chr21-14273688-14274371

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE67783, GSE86191, GSE111913, GSE105028, ENCSR153HNT, GSE68388, GSE25021, ENCSR917QNE

Cell type: MCF-7, H1-hESC, HCT-116, RT-112, K-562, Liver, HSPC, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "13_ReprPC": 20%, "14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, PGR, ZNF660, HMGN3, SOX2, MEIS2, XBP1, PATZ1, FOXA1, SUZ12, RBFOX2, RING1B, UBTF, PBX2, ZFHX2, TFAP4, HDGF, ATF3, NFIC, CHD7, PRDM1, CBFB, ZNF189, SMARCE1, TEAD1, TRIM28, KLF6, LMO2, SAP30, ESR1, OCA2, CTCF, TCF12, BAF155, KLF1, EP300, GATA6, DPF2, E2F6, TRIM24, SOX6, ZNF423, E2F1, TEAD4, EHMT2, TFAP2C, GLIS1, NANOG, CHD8, POU5F1, MYCN, TOP2A, ZNF263, CTBP1, MTA2, ZBTB48, STAT1, SAP130, HIC1, SP4, ERG2, TBP, ERG, MIER1, OGG1, ZNF341, MYC, SMARCA4, KDM4A, ARID1B, FOXP2, GRHL3, GABPA, STAT3, XRCC5, PRDM14, NFE2, HNRNPH1, DACH1, RCOR1, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, GABPB1, SPI1, HDAC2, GATA2, FLI1, MXI1, SMARCA5, NCOA2, RUNX1, CBX1, HDAC1, EZH2phosphoT487, SIN3A, ZFX, ZFP37, TET2, ERG3, CREBBP, ZBTB2, TAF15, SMAD2, ZSCAN30, SP3, ARNT, NRF1, ZNF48, SMAD4, CBFA2T3, NCAPH2, SP2, MED1, GMEB1, SCRT2, PIAS1, L3MBTL2, SETDB1, USF1, SP1, TFAP2A, GSPT2, HNF4A, BCL11A, REST, ZBTB7A, ASH2L, HNRNPLL, PHIP, MBD2, BCOR, AATF, SMC3, NCOR2, STAG1, MLLT1, TRP47, CBFA2T2, FOXA2, TBL1X, CREM, CBX3, AGO1, MTA3, RBBP5, WT1, ZBTB33, ZKSCAN1, YY1, RELA, TARDBP, SP140, ZFP36, HIF1A, SKIL, PCGF1, GATA3, TAL1, MAX, NRIP1, ZNF143, MTA1, AGO2, GATA1, KLF4, NCOA3, NR2F1, KDM5B, PKNOX1, MYOD1, EGR2, ELF3, BRD2, ARRB1, AR, ZNF579, ZBTB40, RXR, EGLN2, ZBTB42, HEXIM1, TFIIIC, HSF1, RNF2, ZBTB26, SCRT1, BRD4, NCOR1, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): HSPA13,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000155304, ENSG00000155313,

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Deatailed information for cohesin site CDBP00413218