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Basic information

CohesinDB ID: CDBP00413224

Locus: chr21-14303731-14304943

Data sourse: GSE138405, GSE206145-GSE177045

Cell type: MCF-7, Hela-Kyoto

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 88%, "14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, PGR, FOXA2, POU5F1, TOP2A, CTBP1, SMAD3, FOXA1, HOXB13, ZNF300, ERG, RELA, CREBBP, MYC, ARNT, HIF1A, GATA3, TAL1, FOXM1, FOS, NR3C1, CEBPB, NR2F2, TEAD1, TCF7L2, NR2F1, EZH2, ESR1, GRHL2, TRPS1, JUN, ELF3, BAF155, EP300, AR, DPF2, GATA2, YAP1, EGLN2, FLI1, RNF2, NOTCH3, BRD4, JUND, CTBP2, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413224