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Basic information

CohesinDB ID: CDBP00413236

Locus: chr21-14376765-14377390

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE25021, GSE108869, ENCSR000BKV, GSE138405, ENCSR703TNG, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR000EDE, GSE50893

Cell type: MCF-7, GM12892, H1-hESC, Hela-Kyoto, HCT-116, Hep-G2, GM12878, GM12891, HeLa-S3, HUES64, GM2255, K-562, SK-N-SH, GM19239, THP-1, GM18486, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 8% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.811

Subunit: SA1,Rad21,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 85%, "5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, PAF1, ZBTB48, DUX4, SRF, ZBTB33, RBFOX2, HOXB13, ZBTB2, OGG1, NEUROD1, MYC, RAD21, PRDM1, SUPT5H, CREB1, ESR1, CTCF, RBM22, TCF12, BCL11A, POU2F3, ILF3, SMC3, NCOR2, STAG1

Target gene symbol (double-evidenced CRMs): USP25,HSPA13,SAMSN1,RBM11,NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530, ENSG00000155313,

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Deatailed information for cohesin site CDBP00413236