- Basic information
- CohesinDB ID: CDBP00413248
- Locus: chr21-14480065-14481269
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Data sourse: GSE98367, ENCSR879KXD, GSE206145, GSE120943, ENCSR000BMY, GSE50893
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Cell type: Monocytes, GM2610, GM12878, K-562, Macrophage, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
46% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, POU2F2, SMC1A, CEBPA, NKX2-2, ID3, HNF1A, STAT1, FOXA1, HOXB13, BCL3, ERG, RELA, TSC22D4, ETS1, NFIC, RAD21, RUNX3, GRHL3, RXRA, ATF2, GABPA, TAL1, NKX3-1, MED1, VDR, NR3C1, JMJD1C, NR2F2, TRIM28, KMT2A, NR2F1, MLL, ELF3, SND1, SPI1, BAF155, SP1, NR4A1, AR, BCL11A, DPF2, POU2F3, FLI1, BRD4, MRTFB, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): SAMSN1,NRIP1
- Function elements
- Human SNPs: Very_long-chain_saturated_fatty_acid_levels_(fatty_acid_20:0)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops