- Basic information
- CohesinDB ID: CDBP00413250
- Locus: chr21-14485378-14486503
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Data sourse: GSE62063, ENCSR198ZYJ, GSE98367
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Cell type: Neurons-H1, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
46% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 66%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, CBX5, SOX2, MEIS2, FOXA1, PBX2, HDGF, TSC22D4, LYL1, BMI1, NFIC, ATF3, RUNX3, CBFB, MECOM, PAX5, TP63, BACH2, CDC5L, MAF, JMJD1C, THRAP3, ELF1, TRIM28, BCLAF1, NFE2L2, LMO2, ESR1, MLL, ZNF217, ZFP91, JUN, CTCF, SND1, TCF12, EP300, DPF2, TRIM24, SOX6, KMT2B, ZNF92, PDX1, RBPJ, EED, POU2F2, CHD8, MYCN, RUNX1T1, ZNF778, MTA2, STAT1, NBN, ARID3A, ERG, NFKB2, ETS1, MYC, SMARCA4, RFX1, ARID1B, RAD21, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, NFE2, VDR, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, GRHL2, SPI1, IRF1, GATA2, FLI1, RELB, RUNX1, SMC1A, BCL6, CEBPA, NKX2-2, SIRT6, LDB1, AFF4, ZFX, MAFG, ZNF18, MEF2A, CREBBP, ZNF384, ZBTB2, NOTCH1, CDK6, ARNT, ATF2, ZEB2, ETV6, FOXM1, MAFB, FOS, CDK8, SUPT5H, MED1, PML, MYB, ZMYM3, SMAD1, C11orf30, L3MBTL2, SETDB1, EVI1, STAT5A, RBM22, MAFK, BCL11A, SP1, NR4A1, REST, RBM25, ATF7, ASH2L, AFF1, TCF3, FOXP1, SMC3, MLLT1, NFATC3, SKI, MEF2B, ZNF316, FOXA2, MTA3, CREM, MEIS1, NFATC1, E2F8, GTF2B, ZBED1, MAFF, MEF2C, ZBTB33, CDK9, BCL3, ZKSCAN1, KDM1A, YY1, RELA, ZNF318, TARDBP, JUNB, ISL1, ZFP36, HIF1A, OTX2, GATA3, BATF, TAL1, MAX, GATA1, HAND2, ZNF592, NR2F2, TCF7L2, ZNF687, PKNOX1, ZNF334, NFKB1, PHOX2B, BRD2, TBX21, BHLHE40, AR, ZBTB16, ZBTB40, RXR, HSF1, MYNN, IKZF2, BRD4, NOTCH3, NCOR1, JUND, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): SAMSN1,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 515
- Number of somatic mutations (non-coding): 0
- Related genes and loops