- Basic information
- CohesinDB ID: CDBP00413254
- Locus: chr21-14497768-14500804
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
45% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, FOXA2, SOX2, DUX4, FOXA1, MEF2C, HOXB13, KDM1A, RELA, MYC, ONECUT1, CHD7, RAD21, GRHL3, OTX2, PRDM9, SMARCE1, TAL1, SUPT5H, CDK8, CEBPB, PML, KMT2A, GRHL2, PHOX2B, RBM22, SPI1, MNT, AR, ZBTB40, RBM25, FLI1, BRD4, FOXP1, ZZZ3, PDX1
- Target gene symbol (double-evidenced CRMs): NRIP1,SAMSN1,HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 755
- Number of somatic mutations (non-coding): 52
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155307,
ENSG00000180530,
- Related loop:
chr21:14050000-14075000~~chr21:14475000-14500000,
chr21:14275000-14300000~~chr21:14475000-14500000,
chr21:14375000-14400000~~chr21:14500000-14525000,
chr21:14475000-14500000~~chr21:14675000-14700000,
chr21:14475000-14500000~~chr21:14725000-14750000,
chr21:14475000-14500000~~chr21:14825000-14850000,
chr21:14475000-14500000~~chr21:14950000-14975000,
chr21:14500000-14525000~~chr21:14600000-14625000,
chr21:14500000-14525000~~chr21:14725000-14750000,
chr21:14500000-14525000~~chr21:14825000-14850000,
chr21:14500000-14525000~~chr21:15150000-15175000,