- Basic information
- CohesinDB ID: CDBP00413260
- Locus: chr21-14518725-14524191
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Data sourse: ENCSR000BLD, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE98367, GSE155324, GSE105028, GSE206145, GSE55407, GSE62063, ENCSR000BMY, ENCSR153HNT, GSE120943, GSE103477, GSE111537, GSE50893, GSE126755, GSE131577
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Cell type: MDM, GM2610, GM19240, OCI-AML-3, H9-hESC, B-cell, GM2630, GM12890, GM2255, K-562, GM18486, H1-hESC, SNYDER, Monocytes, Lymphoblast, GM12878, GM12891, GM2588, GM19239, GM19193, THP-1, Macrophage, Ramos, GM12892, HL-60, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 10% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.700
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 36%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CEBPG, JMJD1C, CEBPB, ATF3, CEBPA, MAF, KMT2A, NR3C1, SOX2, MYB, PDX1, GRHL3, BRD4, ATF4, FOXA1, SUPT5H, MLLT1
- Target gene symbol (double-evidenced CRMs): HSPA13,SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 425
- Number of somatic mutations (non-coding): 20
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155307,
- Related loop:
chr21:14225000-14250000~~chr21:14525000-14550000,
chr21:14375000-14400000~~chr21:14500000-14525000,
chr21:14500000-14525000~~chr21:14600000-14625000,
chr21:14500000-14525000~~chr21:14725000-14750000,
chr21:14500000-14525000~~chr21:14825000-14850000,
chr21:14500000-14525000~~chr21:15150000-15175000,
chr21:14525000-14550000~~chr21:14675000-14700000,
chr21:14525000-14550000~~chr21:14725000-14750000,
chr21:14525000-14550000~~chr21:14750000-14775000,
chr21:14525000-14550000~~chr21:15050000-15075000,
chr21:14525000-14550000~~chr21:25450000-25475000,
chr21:14526513-14528106~~chr21:14545508-14547033,