Deatailed information for cohesin site CDBP00413264

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  • Basic information
  • CohesinDB ID: CDBP00413264
  • Locus: chr21-14537276-14539605
  • Data sourse: GSE98367, ENCSR404BPV, ENCSR879KXD, GSE120943, ENCSR198ZYJ, GSE126755
  • Cell type: Monocytes, Neurons-H1, K-562, Neutrophil, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.944
  • Subunit: SMC3,Rad21,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 41% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 60%, "5_TxWk": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, NME2, MEIS2, FOXA1, RBFOX2, PBX2, HDGF, BMI1, NFIC, ATF3, RUNX3, CHD7, MORC2, SMARCE1, PAX5, HDAC3, BACH2, CDX2, MAF, ZNF629, TEAD1, TRIM28, BCLAF1, KLF6, ELF1, NFE2L2, SMAD5, ESR1, HNF1B, ZNF217, OCA2, CTCF, JUN, TCF12, POU2F1, EP300, DPF2, PAX8, IRF4, RFX5, TRIM24, SOX6, E2F4, RAD51, E2F1, TEAD4, ZNF92, PDX1, RBPJ, EED, POU2F2, POU5F1, ZNF263, TOP2A, RUNX1T1, MTA2, DUX4, ZBTB48, STAT1, SRF, NBN, ARID3A, HIC1, TBP, ERG, HOXC5, ZNF597, SMARCC2, MYC, SMARCA4, ARID1B, RAD21, LHX2, ZNF24, NKX2-1, FOXK2, BATF3, GABPA, STAT3, NKX3-1, IKZF1, NFE2, TERF2, CD74, DACH1, VDR, RCOR1, NR3C1, CEBPB, ESRRA, ZNF750, STAT5B, LEF1, KMT2A, CREB1, EZH2, GRHL2, SPI1, EHF, IRF1, GATA2, GATAD2B, SIX2, FLI1, SMARCA5, RELB, MRTFB, ATF1, CC2D1A, RUNX1, MAFG, BCL6, SMC1A, NKX2-2, HDAC1, EZH2phosphoT487, AFF4, LDB1, CBX1, POU4F2, PALB2, SMAD3, TRIM22, SMARCC1, MEF2A, CREBBP, ZNF384, GATA4, ZNF184, PBX4, NRF1, ARNT, BACH1, DAXX, ATF2, ZEB2, PBX3, ETV6, FOXM1, SUPT5H, CDK8, FOS, SP2, MED1, GMEB1, ZEB1, TERF1, PML, MYB, CEBPD, ZMYM3, SMAD1, NR1H2, C11orf30, GTF3C2, NCOA1, STAT5A, RBM22, NUP98-HOXA9, MAFK, SP1, NIPBL, NR4A1, BCL11A, REST, ZBTB7A, POU2F3, ATF7, ASH2L, ZHX1, PHIP, BCOR, FOXP1, TCF3, SMC3, ELL2, MLLT1, STAG2, NFATC3, ZNF283, TRP47, MEF2B, PPARG, FOXA2, MTA3, CREM, MEIS1, NFATC1, E2F8, ZNF207, CBX3, ZBED1, GTF2B, MAFF, ESR2, CHD2, WT1, ZBTB33, MEF2C, TCF7, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, AHR, CHAMP1, SP140, SKIL, OTX2, GATA3, BATF, TAL1, MAX, GATA1, KLF4, CEBPG, ZNF141, ZNF592, NR2F1, TCF7L2, TP53, PKNOX1, NFKB1, PHOX2B, BRD2, ELF3, TBX21, BHLHE40, AR, ZBTB40, YAP1, ZNF366, RNF2, IKZF2, BRD4, JUND, ILF3, NOTCH3, CLOCK, BRCA1, ADNP, ZNF316, FOSL2
  • Target gene symbol (double-evidenced CRMs): NRIP1,RBM11,SAMSN1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 85
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000185272, ENSG00000155307, ENSG00000180530,
  • Related loop: chr21:14225000-14250000~~chr21:14525000-14550000, chr21:14525000-14550000~~chr21:14675000-14700000, chr21:14525000-14550000~~chr21:14725000-14750000, chr21:14525000-14550000~~chr21:14750000-14775000, chr21:14525000-14550000~~chr21:15050000-15075000, chr21:14525000-14550000~~chr21:25450000-25475000, chr21:14533231-14535623~~chr21:14685023-14689153, chr21:14533236-14535518~~chr21:14762302-14764315,
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