- Basic information
- CohesinDB ID: CDBP00413272
- Locus: chr21-14581372-14582622
-
Data sourse: GSE86191, GSE138405, GSE111913, ENCSR879KXD, GSE206145-NatGen2015, GSE62063, ENCSR153HNT, GSE73207
-
Cell type: Hela-Kyoto, Fibroblast, HCT-116, TF-1, RT-112, K-562, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOSL1, SOX2, MEIS2, HMGN3, FOXA1, RBFOX2, PBX2, UBTF, HDGF, LYL1, ATF3, ATF4, MECOM, SMARCE1, HDAC3, SFPQ, MAF, JMJD1C, ELF1, TRIM28, E2F5, ETV1, NFE2L2, LMO2, SMAD5, JUN, TCF12, EP300, E4F1, LMO1, MNT, GATA6, DPF2, TRIM24, IRF4, SOX6, CREB3, DDX20, E2F1, TEAD4, ZNF175, EHMT2, POU2F2, RUNX1T1, ID3, TOP2A, CTBP1, MTA2, STAT1, NBN, ARID3A, TBP, ERG, SMARCC2, NFKB2, MYC, ONECUT1, SMARCA4, ARID1B, FOXK2, BATF3, GABPA, STAT3, IKZF1, LEF1, RCOR1, NR2F6, NFE2, ZNF639, NFRKB, NR3C1, CEBPB, ESRRA, DACH1, STAT5B, TBL1XR1, EZH2, ZNF652, NFE2L1, PHF8, ELF4, HES1, SPI1, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, TAF9B, FLI1, EP400, ATF1, RUNX1, MAFG, SMC1A, HDAC1, SIRT6, NKX2-2, LDB1, CEBPA, ZFX, ZMIZ1, PRDM10, MYBL2, IRF2, ZNF384, ZBTB2, BRD9, ARNT, BACH1, ATF2, ZEB2, HMBOX1, NFYA, CBFA2T3, FOXM1, FOXJ2, ETV6, CDK8, FOS, SUPT5H, MED1, GMEB1, DIDO1, PML, MYB, CEBPD, ZMYM3, SMAD1, TAF7, C11orf30, L3MBTL2, NCOA1, SETDB1, EVI1, STAT5A, ZNF22, KLF16, MAFK, BCL11A, REST, ZBTB7A, RBM25, CCNT2, ATF7, AFF1, BCOR, TCF3, MBD2, MLLT1, PTTG1, NFATC3, CBFA2T2, CBX3, MTA3, CREM, FOXA2, RBBP5, E2F8, GTF2B, MAFF, ZBTB33, TCF7, HOXB13, ZNF318, KDM1A, ZNF589, RELA, YY1, NEUROD1, ZNF148, CHAMP1, ZNF830, SKIL, HIF1A, GATA3, MGA, TAL1, MAX, GATA1, MTA1, HAND2, KLF4, ZNF592, CEBPG, GFI1B, NR2F2, ZKSCAN8, NR2F1, TCF7L2, KDM5B, PKNOX1, ZNF334, TBX21, AR, PTRF, TAF1, ZBTB16, ZBTB40, EGLN2, HSF1, NCOR1, RNF2, BRD4, JUND, MYNN, NOTCH3, CUX1, ILF3, SCRT1, ZNF24, ADNP, ZNF316
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 102
- Number of somatic mutations (non-coding): 18
- Related genes and loops