- Basic information
- CohesinDB ID: CDBP00413277
- Locus: chr21-14589461-14593131
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Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR230ZWH, GSE98367, ENCSR879KXD, GSE206145, GSE62063, ENCSR000BMY, ENCSR000EDE, GSE120943, GSE68388, GSE103477, GSE111537, GSE50893, GSE126755, ENCSR917QNE
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Cell type: MDM, Macrophage, Monocytes, GM12878, Ramos, GM12891, OCI-AML-3, HeLa-S3, GM2255, K-562, Liver, Neutrophil, THP-1, HuCC-T1, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 59%,
"7_Enh": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, CBX5, SMC1A, MEF2B, POU2F2, MYCN, CREM, MTA3, NFATC1, E2F8, ZNF207, MTA2, DUX4, STAT1, TCF7, NBN, TRIM22, TWIST1, HOXC5, MEF2A, RELA, CREBBP, TARDBP, ZBTB2, ZNF384, JUNB, HDGF, MYC, NFIC, SMARCA4, CHAMP1, ARID1B, ISL1, RUNX3, SKIL, GATA3, ATF2, BATF, TAL1, FOXM1, ETV6, GATA1, CDK8, RCOR1, HAND2, MED1, MAF, ELF1, PML, KMT2A, CREB1, MYB, ZMYM3, PKNOX1, CBX1, USF2, STAT5A, PHOX2B, SPI1, NIPBL, TBX21, EP300, BCL11A, IRF1, DPF2, PAX8, ZBTB7A, IRF4, ATF7, ASH2L, RAD51, NOTCH3, BRD4, RELB, TEAD4, MLLT1, RBPJ
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 39
- Number of somatic mutations (non-coding): 39
- Related genes and loops