- Basic information
- CohesinDB ID: CDBP00413287
- Locus: chr21-14618083-14618876
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Data sourse: GSE98367, ENCSR404BPV, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, GSE50893
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Cell type: Macrophage, Fibroblast, Monocytes, Neurons-H1, GM19240, GM2588, GM2255, GM19239, GM18486
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, FOXA1, CHD7, ATF4, MORC2, JMJD1C, TEAD1, TRIM28, OCA2, JUN, SND1, TCF12, EP300, GATA6, TRIM24, IRF4, TEAD4, RBPJ, TFAP2C, NANOG, POU2F2, POU5F1, BRD3, STAT1, ZNF205, ERG, MYC, SMARCA4, KDM4A, ARID1B, RAD21, GRHL3, NKX2-1, GABPA, STAT3, IKZF1, NFE2, NR3C1, CEBPB, EZH2, SPI1, IRF1, HDAC2, GATA2, FLI1, RELB, MRTFB, ZIM3, RUNX1, CTNNB1, BCL6, NKX2-2, EZH2phosphoT487, SMAD3, TRIM22, SMARCC1, CREBBP, PBX4, ARNT, HMBOX1, MAFB, FOS, CDK8, MED1, MYB, C11orf30, USF1, SP1, NIPBL, ASH2L, BCOR, FOXP1, SMC3, NCOR2, MEF2B, PPARG, ZNF207, FOXA2, RBBP5, EBF1, GTF2B, ZBTB33, CDK9, HOXB13, RELA, TARDBP, JUNB, NEUROD1, BRG1, HIF1A, OTX2, TAL1, GATA1, ZNF143, KLF4, CEBPG, TCF7L2, NFKB1, PHOX2B, TBX21, AR, PAX3-FOXO1, YAP1, BRD4, JUND, ZNF316
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 13
- Number of somatic mutations (non-coding): 13
- Related genes and loops