- Basic information
- CohesinDB ID: CDBP00413291
- Locus: chr21-14637278-14638363
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Data sourse: GSE98367, GSE62063, GSE120943, GSE103477, GSE111537
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Cell type: Monocytes, OCI-AML-3, THP-1, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 93%,
"7_Enh": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, GTF2B, DUX4, MLLT3, MEF2C, CDK9, ERG, YY1, RELA, LYL1, MYC, RAD21, OTX2, TAL1, CDK8, MED1, VDR, JMJD1C, CEBPB, TERF1, MLL, CTCF, SPI1, IRF4, TRIM24, RAD51, BRD4, TEAD4, KMT2B, MLLT1
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops