- Basic information
- CohesinDB ID: CDBP00413302
- Locus: chr21-14674832-14677302
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Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, GSE98367, GSE155324, ENCSR879KXD, GSE206145, GSE62063, ENCSR000BMY, GSE103477, GSE50893, GSE126755
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Cell type: MDM, GM2630, Macrophage, SNYDER, GM10847, GM2610, Lymphoblast, GM12878, Ramos, GM12891, GM2255, K-562, GM19239, Neutrophil, THP-1, GM18486, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, ZNF496, MEIS2, FOXA1, RBFOX2, PBX2, UBTF, TFAP4, HDGF, ZNF274, ATF3, NFIC, RUNX3, ATF4, MECOM, SMARCE1, MITF, HDAC3, BACH2, JMJD1C, MAF, ELF1, TRIM28, E2F5, RBM39, ETV1, NFE2L2, BCLAF1, LMO2, OCA2, HDAC8, JUN, TCF12, CTCF, EP300, E4F1, SND1, ARID5B, GATA6, DPF2, TRIM24, IRF4, SOX6, E2F4, CREB3, RAD51, DDX20, E2F1, TEAD4, KMT2B, ZNF175, GATAD2A, EHMT2, RBPJ, EED, CDK9-HEXIM1, CHD8, POU2F2, BRD3, POU5F1, CDK7, ID3, CTBP1, MTA2, STAT1, NONO, ZNF205, NBN, ARID3A, PHB2, TBP, ERG, SMARCC2, ETS1, MYC, SMARCA4, ARID1B, RAD21, GRHL3, FOXK2, GABPA, STAT3, XRCC5, IKZF1, RCOR1, LEF1, DACH1, NFE2, NR2F6, NFRKB, NR3C1, CEBPB, CD74, TERF2, STAT5B, ESRRA, KMT2A, CREB1, TBL1XR1, EZH2, GABPB1, PHF8, ELF4, SPI1, HES1, IRF1, HDAC2, GATA2, ZNF644, ZSCAN29, FLI1, NR2C2, SMARCA5, EP400, NFYB, ATF1, CC2D1A, RUNX1, MAFG, SMC1A, CEBPA, HDAC1, LDB1, BCL6, ZFX, POU4F2, SMAD3, ZMIZ1, MYBL2, ZBTB2, CREBBP, NOTCH1, BRD9, SMAD2, ZNF184, ARNT, BACH1, ELK1, SMAD4, ZEB2, HMBOX1, CBFA2T3, FOXM1, NR2C1, SUPT5H, CDK8, ETV6, NFYA, FOS, MED1, GMEB1, TERF1, CEBPD, MYB, PML, SMAD1, C11orf30, NCOA1, L3MBTL2, EVI1, STAT5A, KLF16, MAFK, BCL11A, NIPBL, SP1, NR4A1, HNF4A, REST, ZBTB7A, CCNT2, ATF7, ASH2L, AFF1, BCOR, MBD2, FOXP1, TCF3, STAT2, NCOR2, MLLT1, NFATC3, SKI, CBFA2T2, MEF2B, CBX3, MTA3, CREM, FOXA2, MEIS1, RBBP5, E2F8, GTF2B, MAFF, MEF2C, CDK9, HOXB13, KDM1A, ZNF589, RELA, YY1, ZNF148, NEUROD1, JUNB, CHAMP1, ZNF830, ZFP36, SKIL, GATA3, TAL1, MAX, SPIB, GATA1, MTA1, HAND2, CEBPG, ZNF592, ZFP69B, GFI1B, NR2F2, NCOA3, ZNF512, NR2F1, TCF7L2, ZNF687, PKNOX1, PHOX2B, ELF3, BRD2, TBX21, AR, TAF1, ZBTB16, ZBTB40, MYNN, NCOR1, RNF2, BRD4, JUND, HSF1, IKZF2, NOTCH3, MAZ, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): NRIP1,SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 24
- Related genes and loops