- Basic information
- CohesinDB ID: CDBP00413305
- Locus: chr21-14682834-14683407
-
Data sourse: GSE98367, GSE62063, GSE55407
-
Cell type: THP-1, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: SOX2, FOXA1, HDGF, NFIC, CHD7, RUNX3, PRDM1, PAX5, JMJD1C, TRIM28, BCLAF1, LMO2, CTCF, DPF2, IRF4, PDX1, RBPJ, EED, MTA2, DUX4, STAT1, NBN, ARID3A, ERG, MYC, ARID1B, GRHL3, NKX3-1, IKZF1, NR3C1, CEBPB, KMT2A, SPI1, FLI1, SMARCA5, RELB, RUNX1, BCL6, SMC1A, CEBPA, TRIM22, MEF2A, ZNF384, PRDM9, ETV6, CDK8, MED1, MYB, ZMYM3, BCL11A, NIPBL, NR4A1, REST, ZBTB7A, ATF7, TCF3, BCOR, NCOR2, MLLT1, NFATC3, EBF1, GTF2B, MEF2C, CDK9, KDM1A, RELA, TARDBP, JUNB, TAL1, MAX, SPIB, GATA1, ZNF143, ZNF592, ZNF512, PKNOX1, PHOX2B, TBX21, AR, TAF1, ZNF366, NCOR1, IKZF2, BRD4, CUX1, ZNF24
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops