- Basic information
- CohesinDB ID: CDBP00413307
- Locus: chr21-14690877-14693534
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Data sourse: GSE67783, GSE98367, GSE206145-NatGen2015, GSE62063, GSE120943, ENCSR153HNT, GSE68388, GSE126755
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Cell type: Fibroblast, Monocytes, HuCC-T1, K-562, Neutrophil, HSPC, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, POU2F2, MEF2B, CEBPA, POU5F1, NKX2-2, CHD2, ID3, ZNF335, ZNF534, FOXA2, ZNF692, DUX4, EBF1, STAT1, SRF, MEF2C, NBN, PBX2, RBFOX2, ERG, HOXC5, RELA, ASCL1, ZNF148, ATF3, MYC, JUNB, CHAMP1, NEUROD1, ARID1B, ZNF830, GRHL3, PBX4, DAXX, HIF1A, OTX2, ATF4, ZEB2, STAT3, MAX, MAFB, NKX3-1, FOS, CDK8, RCOR1, NFE2, ZNF660, MED1, NR3C1, CEBPG, CEBPB, NCOA3, JMJD1C, TRIM28, MYB, CEBPD, GFI1B, TCF7L2, ESR1, KLF9, C11orf30, NFKB1, PHOX2B, JUN, SPI1, EP300, BCL11A, NR4A1, AR, EHF, DPF2, ZBTB40, GATA2, TRIM24, FLI1, BRD3, BRD4, JUND, PDX1, ZNF316
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 17
- Related genes and loops