- Basic information
- CohesinDB ID: CDBP00413309
- Locus: chr21-14699551-14700993
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Data sourse: GSE206145-GSE177045, GSE72082, GSE76893, GSE68388, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, HuCC-T1, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 89%,
"7_Enh": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, NFIA, PGR, HMG20A, HNF1A, FOXA1, RXRB, PBX2, KDM3A, TFAP4, MEN1, ATF3, NFIC, SMARCE1, MITF, HDAC3, CDX2, TEAD1, TRIM28, ELF1, KLF6, RCOR2, ZNF217, HNF1B, ESR1, OCA2, JUN, TCF12, EP300, BAF155, SOX9, GATA6, SOX5, DPF2, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, EHMT2, TFAP2C, NANOG, HHEX, TOP2A, ID3, CTBP1, MTA2, SRF, GATAD1, SAP130, ARID3A, HNF4G, ERG, MYC, ONECUT1, RAD21, RXRA, NKX2-1, STAT3, ZNF614, NKX3-1, LEF1, MIER3, NR2F6, VDR, NR3C1, CEBPB, ESRRA, CREB1, TBL1XR1, GRHL2, TRPS1, SPI1, MIXL1, EHF, IRF1, HDAC2, GATA2, ZNF644, ZGPAT, NFIL3, NCOA2, RUNX1, THAP11, CTNNB1, MAFG, BCL6, CEBPA, EZH2phosphoT487, SOX13, SIN3A, SMAD3, TBX3, SP5, SMARCC1, MYBL2, RARA, CREBBP, NOTCH1, ZXDC, RUNX2, GR, PBX4, ARNT, PRDM9, FOXM1, MED1, CSNK2A1, TEAD3, MYB, PIAS1, C11orf30, L3MBTL2, SP1, NIPBL, TFAP2A, HNF4A, REST, ARID1A, ASH2L, CTBP2, MBD2, FOXP1, STAG1, SKI, ZNF316, FOXA2, PPARG, CREM, ZBTB33, TCF7, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, BRG1, ZFP36, HIF1A, GATA3, MAX, NRIP1, TLE3, CEBPG, KLF4, NR2F2, NR2F1, KDM5B, TP53, PKNOX1, ZNF334, T, ELF3, KAT8, NFKBIZ, AR, BHLHE40, ARID4B, YAP1, RNF2, NCOR1, BRD4, JUND, CUX1, SMAD4.1D12, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops