- Basic information
- CohesinDB ID: CDBP00413311
- Locus: chr21-14711877-14712586
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, GSE101921, GSE112028, ENCSR703TNG, GSE25021
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Cell type: MCF-7, HeLa-Tet-On, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 78%,
"9_Het": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, MEIS2, FOXA1, PBX2, MEN1, CHD7, SMARCE1, TEAD1, KLF6, ETV1, ZNF217, ESR1, HNF1B, LMO2, JUN, TCF12, EP300, DPF2, SOX6, SMC1, TEAD4, TFAP2C, CTBP1, HNF4G, PAX6, MYC, RAD21, LHX2, GRHL3, STAT3, NR3C1, ESRRA, CEBPB, CREB1, GRHL2, TRPS1, IRF1, HDAC2, GATA2, GATAD2B, FLI1, NCOA2, RUNX1, SMC1A, SIN3A, SMAD3, CREBBP, ZXDC, RUNX2, GR, ARNT, PBX4, FOXM1, FOS, CDK8, MYB, ZNF680, SETDB1, NIPBL, ATF7, CTBP2, MBD2, STAG1, FOXA2, RELA, HIF1A, OTX2, GATA3, TAL1, NRIP1, KLF4, NCOA3, NR2F2, TCF7L2, NR2F1, TP53, PKNOX1, MYOD1, ELF3, AR, BRD4, JUND, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops