- Basic information
- CohesinDB ID: CDBP00413315
- Locus: chr21-14722832-14723504
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Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, ENCSR000BMY, GSE97394, GSE50893
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Cell type: HUES64, GM12878, GM12891
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 90%,
"9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, NANOG, MEF2B, SMC1A, ZNF207, POU5F1, CBX5, POU2F2, EBF1, E2F8, ZNF316, MTA2, ZBED1, TOP2A, FOXA1, TCF7, NBN, TRIM22, ERG, MEF2A, TARDBP, NOTCH1, JUNB, BMI1, MYC, NFIC, CHD7, RUNX3, ARNT, SKIL, RAD21, BACH1, CBFB, ATF2, BATF3, BATF, FOXK2, GATA3, ETV6, PAX5, GABPA, GATA1, IKZF1, MED1, KLF5, ELF1, BCLAF1, TRIM28, STAT5B, MYB, ZNF217, ZNF687, CTCF, TCF12, NIPBL, SPI1, TBX21, BHLHE40, BCL11A, EP300, DPF2, IRF4, GATAD2B, ATF7, RAD51, IKZF2, JUND, SMARCA5, BCOR, NCOR1, RELB, SMC3, ZNF24, MLLT1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
- Related loop:
chr21:14225000-14250000~~chr21:14725000-14750000,
chr21:14250000-14275000~~chr21:14725000-14750000,
chr21:14275000-14300000~~chr21:14725000-14750000,
chr21:14400000-14425000~~chr21:14725000-14750000,
chr21:14425000-14450000~~chr21:14725000-14750000,
chr21:14450000-14475000~~chr21:14700000-14725000,
chr21:14450000-14475000~~chr21:14725000-14750000,
chr21:14475000-14500000~~chr21:14725000-14750000,
chr21:14500000-14525000~~chr21:14725000-14750000,
chr21:14525000-14550000~~chr21:14725000-14750000,
chr21:14600000-14625000~~chr21:14725000-14750000,
chr21:14725000-14750000~~chr21:14850000-14875000,
chr21:14725000-14750000~~chr21:15475000-15500000,
chr21:14725000-14750000~~chr21:15575000-15600000,