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Basic information

CohesinDB ID: CDBP00413318

Locus: chr21-14733859-14734983

Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, GSE98367, ENCSR000BMY, GSE120943, GSE103477, GSE50893

Cell type: MDM, GM12892, GM2630, Macrophage, Monocytes, GM2610, GM19240, GM12878, GM2588, GM19238, GM2255, GM19193, GM18486

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SMC3,Rad21,SA1,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 41% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 86%, "7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, RUNX1, SKI, FOSL1, SMC1A, CEBPA, POU5F1, CREM, GTF2B, STAT1, FOXA1, MLLT3, ZBTB33, MEF2C, SRF, TRIM22, KDM1A, ERG, RELA, ZBTB2, TARDBP, ZNF384, YY1, JUNB, CHAMP1, RUNX3, RAD21, PRDM1, SKIL, SMARCE1, ETV6, GATA1, CDK8, IKZF1, FOS, ELF1, TRIM28, MYB, KMT2A, ESR1, MLL, ZNF41, CTCF, SPI1, NIPBL, TBX21, NR4A1, AR, BCL11A, DPF2, ATF1, GATA2, REST, ATF7, IKZF2, JUND, BRD4, RELB, TEAD4, ZNF24, RBPJ, EED

Target gene symbol (double-evidenced CRMs): RBM11,SAMSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155307,

eachgene

Deatailed information for cohesin site CDBP00413318