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Basic information

CohesinDB ID: CDBP00413320

Locus: chr21-14741240-14741827

Data sourse: ENCSR000BTU, GSE72082, GSE98367, GSE68388, ENCSR703TNG

Cell type: MCF-7, Macrophage, Ishikawa, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 41% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 95%, "7_Enh": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, MEIS2, FOXA1, PBX2, ATF3, NFIC, ZNF189, DPF1, MITF, TEAD1, TRIM28, ESR1, USF2, JUN, ZNF507, TCF12, EP300, BAF155, MNT, DPF2, TEAD4, PDX1, TFAP2C, GLIS1, ARID3A, HIC1, ERG, OGG1, MYC, EOMES, ARID1B, RAD21, GRHL3, GABPA, STAT3, NKX3-1, IKZF1, RCOR1, NR2F6, NR3C1, CEBPB, CREB1, EZH2, KLF8, HDAC2, GATA2, NR2C2, MXI1, ZBTB24, SIRT6, NKX2-2, SMAD3, PRDM10, CREBBP, OSR2, ZNF184, PBX4, DAXX, ARNT, HMBOX1, CBFA2T3, NR2C1, FOS, CDK8, MYB, PIAS1, L3MBTL2, USF1, BCL11A, SP1, RBM25, PHIP, ZNF316, FOXA2, WT1, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, JUNB, CHAMP1, OTX2, GATA3, TAL1, MAX, GATA1, TLE3, ZNF592, SP7, NR2F2, NR2F1, TCF7L2, T, TBX21, AR, BRD4, JUND, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SAMSN1,RBM11

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155307,

eachgene

Deatailed information for cohesin site CDBP00413320