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Basic information

CohesinDB ID: CDBP00413321

Locus: chr21-14742627-14743253

Data sourse: GSE62063, ENCSR879KXD, GSE98367

Cell type: K-562, Macrophage, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 41% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 95%, "9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, CEBPA, POU5F1, TOP2A, WT1, ZBTB33, KDM1A, MIER1, NFIC, PBX4, OTX2, ZEB2, CEBPG, ZNF592, ZNF512, ZNF507, SPI1, HDAC2, ZBTB40, BRD4, PHIP, SRSF9, TEAD4, MLLT1

Target gene symbol (double-evidenced CRMs): RBM11,SAMSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155307,

eachgene

Deatailed information for cohesin site CDBP00413321