- Basic information
- CohesinDB ID: CDBP00413329
- Locus: chr21-14766150-14766779
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Data sourse: ENCSR000BLD, GSE104888, GSE72082, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE131606, GSE108869, GSE25021, ENCSR000BTU, GSE93080, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE152721, GSE116344, GSE106870, GSE145327, ENCSR000EEG, ENCSR338DUC, ENCSR000BLS, ENCSR000ECE, GSE97394, ENCSR167MTG, GSE110061, GSE129526, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE126990, GSE50893
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Cell type: MDM, RH4, CVB-hiPSC, CVI-hiPSC, HuCC-T1, H9-hESC, Ishikawa, GM12890, HeLa-S3, K-562, GM18486, DKO, GM18526, H1-hESC, GM18951, GM12878, GM12891, SK-N-SH, GM19239, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, GM19238, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.700
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 91%,
"14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, BCL6, CBX1, CBX3, SMC1A, CHD8, POU5F1, TEAD4, WT1, SMAD3, SRF, ZBTB33, KDM1A, ERG, RELA, ZBTB2, YY1, MYC, CHAMP1, CTCFL, RAD21, ARNT, HIF1A, ATF2, XRCC5, MAX, ZNF143, CEBPG, ZNF592, TRIM28, CREB1, ESR1, CTCF, RYBP, E2F6, ZNF644, EGLN2, BRD4, SMC1, SMC3, STAG1, CC2D1A
- Target gene symbol (double-evidenced CRMs): RBM11,SAMSN1,HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000185272,
ENSG00000155304,
ENSG00000155307,
- Related loop:
chr21:14225000-14250000~~chr21:14750000-14775000,
chr21:14250000-14275000~~chr21:14750000-14775000,
chr21:14275000-14300000~~chr21:14750000-14775000,
chr21:14375000-14400000~~chr21:14750000-14775000,
chr21:14400000-14425000~~chr21:14750000-14775000,
chr21:14425000-14450000~~chr21:14750000-14775000,
chr21:14450000-14475000~~chr21:14750000-14775000,
chr21:14525000-14550000~~chr21:14750000-14775000,
chr21:14533236-14535518~~chr21:14762302-14764315,
chr21:14750000-14775000~~chr21:14850000-14875000,