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Basic information

CohesinDB ID: CDBP00413330

Locus: chr21-14768089-14768942

Data sourse: GSE72082, GSE98367, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, ENCSR703TNG

Cell type: MCF-7, Fibroblast, Monocytes, K-562, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 93%, "14_ReprPCWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, FOSL1, MEF2B, HDAC1, CREM, ZFX, CTBP1, MTA2, DUX4, FOXA1, MEF2C, ZBTB33, SUZ12, ARID3A, TRIM22, PBX2, MEF2A, RELA, CREBBP, TARDBP, HDGF, JUNB, ATF3, RUNX3, RAD21, GRHL3, SKIL, ATF2, GATA3, BATF, FOXM1, ZSCAN4, FOS, IKZF1, CDK8, NR2F6, ESRRA, CEBPB, ELF1, TEAD1, ZNF217, ESR1, GRHL2, JUN, BCL11A, TBX21, AR, DPF2, REST, GATAD2B, TRIM24, ATF7, FOSL2, IKZF2, BRD4, JUND, RELB, ZNF24, EED

Target gene symbol (double-evidenced CRMs): RBM11,HSPA13,SAMSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 18

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307,

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Deatailed information for cohesin site CDBP00413330