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Basic information

CohesinDB ID: CDBP00413331

Locus: chr21-14771132-14775232

Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE101921, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, GSE94872, ENCSR000EEG, ENCSR338DUC, GSE115248, GSE105004, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE131577, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, GSE206145, GSE85526, ENCSR000ECE, ENCSR767DFK, GSE55407, ENCSR000BTQ, GSE129526, ENCSR000BLY, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990

Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, HEKn, THP-1, Ishikawa, Kelly, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, TC-71, Neutrophil, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 55% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.233

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 86%, "9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, CBX1, FOXA2, SIN3A, CTBP1, ZNF317, FOXA1, HOXB13, ERG, CREBBP, AHR, MYC, RAD21, ARNT, HIF1A, NKX2-1, GATA3, ZEB2, GABPA, MAFB, NRIP1, GATA1, NR3C1, ZNF592, ESRRA, NR2F2, TRIM28, MYB, NR2F1, SNAI2, STAG1, ZNF217, ESR1, GRHL2, TRPS1, JUN, EP300, TFAP2A, BAF155, MNT, AR, DPF2, HDAC2, GATA2, EGLN2, SOX6, ASH2L, NCOR1, CTBP2, FOXP1, PDX1, TFAP2C

Target gene symbol (double-evidenced CRMs): NRIP1,HSPA13,SAMSN1,RBM11

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 18

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413331