- Basic information
- CohesinDB ID: CDBP00413337
- Locus: chr21-14824996-14827058
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Data sourse: ENCSR000EAC, ENCSR000DZP, GSE155324, ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR000BMY, GSE50893
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Cell type: GM2630, Fibroblast, SNYDER, GM10847, Lymphoblast, GM19240, GM12878, GM12891, GM2255, GM19239, GM19193, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: Mau2,SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 95%,
"7_Enh": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, RUNX1, POU2F2, MEF2B, SMC1A, HDAC1, MTA3, CREM, EBF1, NFATC1, RUNX1T1, MTA2, GTF2B, FOXA1, ZNF205, TCF7, NBN, ARID3A, TRIM22, BCL3, PRDM10, HNRNPK, MEF2A, RELA, HDGF, TARDBP, YY1, ZNF597, JUNB, TSC22D4, NFIC, MYC, ARID1B, RUNX3, PRDM1, SKIL, ATF2, BATF3, BATF, TAL1, FOXM1, CBFA2T3, MAX, GATA1, IKZF1, MED1, BACH2, PML, BCLAF1, TRIM28, CREB1, ZMYM3, SMAD1, ZNF687, NFKB1, STAT5A, ZFP91, CTCF, TCF12, RBM22, BCL11A, SPI1, TBX21, SP1, SND1, IRF1, DPF2, HDAC2, IRF4, ATF7, ASH2L, RAD51, IKZF2, BRD4, HSF1, RELB, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): SAMSN1,HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155307,
- Related loop:
chr21:14375000-14400000~~chr21:14825000-14850000,
chr21:14400000-14425000~~chr21:14825000-14850000,
chr21:14475000-14500000~~chr21:14825000-14850000,
chr21:14500000-14525000~~chr21:14825000-14850000,
chr21:14825000-14850000~~chr21:15475000-15500000,
chr21:14825000-14850000~~chr21:15500000-15525000,
chr21:14825000-14850000~~chr21:15575000-15600000,
chr21:14825021-14827663~~chr21:15552007-15554258,