- Basic information
- CohesinDB ID: CDBP00413351
- Locus: chr21-14886972-14889717
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Data sourse: ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR404BPV, GSE25021, ENCSR000EDW, ENCSR917QNE, GSE165895, GSE76893, ENCSR198ZYJ, GSE116344, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR768DOX, ENCSR000BLS, ENCSR981FDC, ENCSR247LSH, ENCSR620NWG, ENCSR767DFK, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR335RKQ, ENCSR054FKH, GSE68388, ENCSR748MVX
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Cell type: RH4, Hep-G2, Neurons-H1, A-549, Liver, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 65%,
"7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, LCORL, SOX2, MEIS2, HNF1A, FOXA1, HLF, PBX2, RXRB, KDM3A, TFAP4, TSC22D4, THRB, NFIC, ATF3, ZFP64, RUNX3, PRDM1, CBFB, MXD4, SMARCE1, ZNF736, CDX2, TEAD1, TRIM28, KLF6, ETV1, RCOR2, ESR1, HNF1B, LMO2, OCA2, MLL, TP73, MBD4, JUN, CTCF, TCF12, EP300, L3MBTL4, MNT, GATA6, SOX5, DMAP1, RFX3, TEAD4, FOXA3, ZNF175, GATAD2A, TFAP2C, RBPJ, MLX, EED, POU2F2, POU5F1, BRD3, TOP2A, HHEX, RUNX1T1, STAT1, GATAD1, SAP130, BAHD1, ARID3A, HNF4G, ERG, SMARCC2, ETS1, MYC, ONECUT1, HOMEZ, RAD21, LHX2, ARID1B, RXRA, PROX1, FOXK2, GABPA, STAT3, ZNF614, XRCC5, IKZF1, MIER3, TCF25, DACH1, NR2F6, ARNTL, DNMT3B, NR3C1, CEBPB, VDR, ZNF750, CREB1, TBL1XR1, ZNF652, GABPB1, ZHX2, SPI1, MIXL1, TFE3, HBP1, IRF1, HDAC2, GATA2, SSRP1, ZNF644, FLI1, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, NKX2-2, AFF4, SOX13, SMAD3, PALB2, TBX3, SP5, SMARCC1, PRDM10, MYBL2, RARA, ZNF384, NFYC, CREBBP, RUNX2, CDK6, GR, PBX4, ARNT, DAXX, ZNF48, PRDM9, SMAD4, CBFA2T3, FOS, CDK8, SMARCB1, HMGXB4, MED1, TEAD3, ZEB1, CEBPD, ZNF3, NR1H2, MBD1, RBM22, SP1, NIPBL, BCL11A, HNF4A, IKZF5, REST, ARID2, ATF7, ASH2L, PHIP, TCF3, FOXP1, SMC3, ELL2, SKI, PPARG, FOXA2, CREM, MIER2, WT1, ZBTB33, TCF7, HOXB13, ZNF580, FOXO3, KDM1A, YY1, RELA, ZKSCAN1, JUNB, KAT2B, HIF1A, OTX2, GATA3, TAL1, MAX, HAND2, CEBPG, NR2F2, TP53, PKNOX1, ELF3, KAT8, NFKBIZ, AR, ARID4B, BHLHE40, ZBTB40, YAP1, EGR1, ZBTB26, NCOR1, HSF1, BRD4, JUND, CUX1, TBX2, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NRIP1,USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14875000-14900000~~chr21:14975000-15000000,
chr21:14875000-14900000~~chr21:15000000-15025000,
chr21:14875000-14900000~~chr21:15025000-15050000,
chr21:14875000-14900000~~chr21:15050000-15075000,
chr21:14875000-14900000~~chr21:15150000-15175000,
chr21:14875000-14900000~~chr21:15200000-15225000,
chr21:14875000-14900000~~chr21:15225000-15250000,
chr21:14875000-14900000~~chr21:15275000-15300000,
chr21:14875000-14900000~~chr21:15450000-15475000,
chr21:14875000-14900000~~chr21:15475000-15500000,
chr21:14875000-14900000~~chr21:15725000-15750000,
chr21:14875000-14900000~~chr21:16775000-16800000,
chr21:14875000-14900000~~chr21:27500000-27525000,