- Basic information
- CohesinDB ID: CDBP00413353
- Locus: chr21-14892252-14892703
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Data sourse: GSE206145-NatGen2015, ENCSR153HNT
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Cell type: K-562, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 93%,
"5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, PAX3-FOXO1, NR3C1, ZFP69B, POU2F2, CHD8, TRIM28, CDK6, EZH2, ZSCAN16, GTF2B, BRD4, NOTCH3, ZBTB26, GRHL3, GABPA, CTCF, BCL11A, ETV5, KDM1A
- Target gene symbol (double-evidenced CRMs): USP25,NRIP1
- Function elements
- Human SNPs: Depression_in_smokers
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14875000-14900000~~chr21:14975000-15000000,
chr21:14875000-14900000~~chr21:15000000-15025000,
chr21:14875000-14900000~~chr21:15025000-15050000,
chr21:14875000-14900000~~chr21:15050000-15075000,
chr21:14875000-14900000~~chr21:15150000-15175000,
chr21:14875000-14900000~~chr21:15200000-15225000,
chr21:14875000-14900000~~chr21:15225000-15250000,
chr21:14875000-14900000~~chr21:15275000-15300000,
chr21:14875000-14900000~~chr21:15450000-15475000,
chr21:14875000-14900000~~chr21:15475000-15500000,
chr21:14875000-14900000~~chr21:15725000-15750000,
chr21:14875000-14900000~~chr21:16775000-16800000,
chr21:14875000-14900000~~chr21:27500000-27525000,