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Basic information

CohesinDB ID: CDBP00413355

Locus: chr21-14900078-14901068

Data sourse: GSE206145, GSE206145-NatGen2015, GSE135093, ENCSR153HNT, GSE68388

Cell type: RPE, Fibroblast, IMR-90, K-562, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 78%, "7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, HNF1A, FOXA1, MLL4, ATF3, NFIC, RUNX3, CBFB, CDX2, MAF, TEAD1, BCLAF1, ZNF26, SNAI2, NFE2L2, KLF6, ESR1, HNF1B, TP73, OCA2, JUN, TCF12, EP300, DPF2, IRF4, TEAD4, EED, POU2F2, STAT1, SRF, HOXC5, PAX6, ETS1, MYC, SMARCA4, RAD21, LHX2, GRHL3, PROX1, NKX2-1, RXRA, GABPA, STAT3, IKZF1, RCOR1, NFE2, ZNF285, ARNTL, NR3C1, CEBPB, VDR, STAT5B, KMT2A, ZHX2, SPI1, IRF1, HDAC2, GATA2, ZNF644, SIX2, RELB, RUNX1, CTNNB1, NKX2-2, EZH2phosphoT487, SIN3A, ZFX, AFF4, SMAD3, TRIM22, SMARCC1, RUNX2, CDK6, GATA4, OSR2, PBX4, DAXX, ARNT, ATF2, ETV6, MAFB, FOS, CDK8, MED1, ZEB1, NR1H2, C11orf30, MAFK, NIPBL, SP1, BCL11A, HNF4A, ATF7, PHIP, PPARG, CBX3, CREM, GTF2B, TCF7, HOXB13, RELA, JUNB, TCF4, HIF1A, OTX2, BATF, TAL1, MAX, KLF4, SP7, GFI1B, TCF7L2, NEUROG2, TP53, NFKB1, MYOD1, ELF3, T, BRD2, BHLHE40, PAX3-FOXO1, AR, YAP1, RXR, ZNF366, HSF1, IKZF2, BRD4, JUND, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413355